In September 1994 SPIFF joined the Polish Chamber of Commerce and two years later the Director of the Association became a member of the board of PCC.
Since 1994 SPIFF has cooperated with the European Federation of Pharmaceutical Industries and Associations (EFPIA) in Brussels and in May 2004 it became a full member. SPIFF was also a part of the International Federation of Pharmaceutical Manufacturers and Associations (IFPMA) based in Geneva.
In August 2006 the member companies of the Association of Representatives of Innovative Pharmaceutical Companies established the Employers' Association of Innovative Pharmaceutical Companies INFARMA.